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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb5522bfce009b7f578d8ad3ba584e1e9926c941271104c8fed27adee0a672d6' 
  AND token = 'eWyt1hqdFsABs1HCHW+TZZhTiSnVKT/h4x6a6c2DWwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}