SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9cf8eaacd41c1467a29c65f708840a1b298bb8380c62885c677003043f15d1' 
  AND token = 'XB7dUlBUYavyYgjsfTS7OEZCzOU3jQIYCyTwdE+rAno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}