SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2d6084a83d19417a33e623d3f3f613a441e83c0588a33c1279f86420f24759' 
  AND token = '5dr4zcTPeQSCrbSV4njrIyXjn+SyZcHr8CHVgPU3p/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}