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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c693076a5fdf9e6e1107f067c4e38b9769b9c33fa681a957bc07cb40a841ceb' 
  AND token = '73UIQgaW0MH3RJvtT4mkD1IboDoS7e77lKRWHdi+eFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}