SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ee283f0d57b94bd101dcb2bc97268a89833c79d7b1baaa3c0e13d63d35a1c9' 
  AND token = 'XXngJcYd4bBNmS87xb/GdLi47uI86C1uP/rK5XkNtzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}