SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9e311045c283c23f42a511c033616c8f7ba03a7eb8fc13cc9d70a75b11a1aa' 
  AND token = 'k5uRCRdmb9NTizFl6DhMRhCC7SgzSHNUjnhFbkqIUAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}