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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c59344968441b08f708b0010b6284e7e1a437e560a2a12e4389f4f0556bf41' 
  AND token = 'Jw3aG4j2s9KRH5Bzq6yDveuc+NYrO0E4n7kwSXyTBzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}