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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46a741540f27c0088cd5c62dc8a84e100b0e99098f2b12686e95e36f9b7a15c' 
  AND token = 'D0/z2F52WveI9g882ZKWyoBSS4YDTz9bRcjrhR5TkYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}