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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac93094dc1e462a76f9d80a9c3e0b995880efdd7b660314921f238cede0cb21' 
  AND token = 'UI5wnQHt3vr3lFdOOikh4pbLtmoEqoFzYqBUj9/pHAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}