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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9c7ebc53720de2ef2735f25f636b26f615081f34eed0fdc48563427627f48bf' 
  AND token = 'WZd29d+sz2ZP0fgj4QOAjYYfhP53Uja8Dzu5RvygdkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}