SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0b844d63961ee3f15219205ea15a00f0d35b4cfc657e0ac774059da3af5be36' 
  AND token = '8B4s6xICvKuWglmSyDrAvX85WOzhOORPCeFHZi/aI48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}