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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463b364ae7080f140e957b2ca4c65ee11340c56dfb1a8d47b7b06590c6f14bdc' 
  AND token = '33vHpAKa6uwozKWZJMSrSdhRjuva8gcylPGC6bWCVD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}