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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c932f50821a21bf289b5264eab37d35b00050b11fdfe7bc49c702468ce5319e' 
  AND token = '8hUrE6wwCUYe/h3h6dLAkmhsitGt8uRAzs2L/HbY0j4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}