SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd905ea2e7f2d3b9148657b000c82a496065271b546f77580b753a912c404d05f' 
  AND token = 'pOcGX1IAGRGGmtf3BIUtA4Tdtia+f/5CwMrnqwbAZiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}