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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c1eafe4286823971e6de8afc5e1c9c5ec820e29590fc840fd16a20adb05d56' 
  AND token = '12EPqErAV6gBHSxlmxibtahhM+CxjygSZH6cR4e1zxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}