SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ea7f348f0cf7a82f6e7923f1312f67a076017a6788f305f89019aac56a0f93' 
  AND token = 'MT/08e4CVoorB/s6LnF7bpSowS1zZJsv8X3HevrR0kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}