SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dbcdf40eed6221f6bf89be825df70ba646200463902c02f8a8ce10c39fe6dac' 
  AND token = 'carwNpRrVPGTVfnE+qQtkd9FgATus0JczvsGzHc8wV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}