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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374f749be02bae87fef4c7c1a95aba038e4b91f0b19cb43a135e528991721c07' 
  AND token = '56WZH97hd67cFybxfU31jhPOv85bXPowW7pueCXGWBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}