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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1e4f9b4fe0f64f3c90c4814f7c3a1ab89fd80c5980f25410db48970d7e224a' 
  AND token = 'qeHjrA3SvmH/ZwN86M1kZbsvsLUUO09ityEtOpncrpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}