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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa3008baaa6a6e4f7b8164bcb81800752187b6f00d41018003d8b8adb153b191' 
  AND token = 'kpKXe2c4wnD/dtN8jT6qrlUIS9ZiTOn0pEo52tKBzbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}