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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da573a5afb3b96acf6ea8dbfb885e14da9cca4b5b41608071406143267fe9cb' 
  AND token = 'veTeDFaA8dFId7WgCw/QsIT3h7oBqHay7ePFP4mJIac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}