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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc1578e330339263f0ee41aa440f608f3c3d43417c3ecbb69872e9a33cb749c5' 
  AND token = '8CXFX9cap7zNqOSCeBHXIWe8MGgNrdN6hOa0tseZWW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}