SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3a0aa4486f6a76fde10c3da27f119213e04a5f24786334474621baf6469a9a' 
  AND token = 'xo/v3hHaj8wkA0tZYs5YGIt6gXkUxw2KHw8N1mKXZc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}