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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a1a4f3bcd375312456eb6cb13ca7d290cf711013ae3e1d84aabd75db732e5d' 
  AND token = 'UNd4BZ2SMWsDt2SuIrvLBQf0KyCkdpueoNW8bo0F45o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}