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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c440d8c205f3696f759c18d3e1b6f8eb628b83768d107b4b09054ba8a984ce29' 
  AND token = 'qVXpjmfae17onIDqatxjzO1gz10GP1GChv3iMynVTys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}