SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af3663af7527288867fd09920b969c8a182ec679d216d3442c2f76a4c72f72f' 
  AND token = 'IzJxCod/khspyXlXzMoBY4pdOTOc0lJi9zgh2i2HfaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}