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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e08ed9520d6610c8b7f23e1b0867fceff49b8d2bd621fb604d12284f380a47' 
  AND token = 'Lu2n5afjpZMn7KVz664K5/5vHyknMqgTnc8r43EQOtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}