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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f6353bab7471b9b8959866d3fcfcf1e2923fe81557ad2163a2fd76d70c03a6' 
  AND token = 's4SgCpNU2wGxBExFq21qKRsn5JqMlp5D1q2fyHS3Vdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}