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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5064a59f118c00b5abeab52aff279dad309224adb5bfe525e9b5bbbd9f90bb92' 
  AND token = '0e6OkqhgztFIwHj/h0VgDh5OqS2HTMT1xp6oRb/9e3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}