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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '874fb9e798b76ac6d0838baacc2f941e9d1689bf5def56e4c5f3d1e3072c6c1e' 
  AND token = 'O/enaTgFw23FbVAQy/rOoDSWK2ikgCAM7SPvkdnnDIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}