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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bf4fe7523e937e9ee1cf49df8b8b982226dba55d11cca872e8a287c017004df' 
  AND token = '1Y+MH7yCvVaFM7+QrrtTwRJKiTgyB1XpFMOC3OsIe5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}