SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002c1dfd4a886ab01532b2b51f8858782fec17a932a57c4c44d203183e2e3591' 
  AND token = 'mqQEDS3gL06e3OCEThJSpntZJzyRN2M9w9KbygqsLQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}