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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201cfe2f26218d2e0885653566779aed191ee7b68df2645720978595623bf007' 
  AND token = 'XbeGZq+G05pS4Y82gaeRO1VHXuYoTgpahi9s1jyjrYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}