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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1a3ec567189b9a0b21b85c60681200e3902181cb5d0ca130279e1eeca9ff1d' 
  AND token = 'j75vfIJvBOQ+pZEZ80qn7vYgBPZWtng+N+g9n0zBsi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}