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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e52d5eb8c4e6662bc062efa75c45d0e878153b57f5bca7da7fbdca664663b38' 
  AND token = 'bxWUYUKnVzsUPMjYu87l7tsCq90k71UDSpAn4NI5S1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}