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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2592bbfbd012b33c390e13b79ba1cc4df037ed4b132f2d274f86b1a21a2273' 
  AND token = 'fNoVZQYvkJuxtLrm15AQ7Ja/k99aQDBdQvIpB2N9v6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}