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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f887d701353f0d7e5f182b71e7791c32c8da82bf55e218b6202316e2cc33898' 
  AND token = '/nUpVyrU/afD1Cwbm7ybRu/DgrU38IRPUaEtK7bCOF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}