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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd260ee73004014b6bd71232bc6c4c639cef4bb2b406c2fea6a1d4e251476f29e' 
  AND token = 'IeQO3JumbSWL8lEquo/HZOWhbH9pMI3vW41OV369cPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}