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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43ca9e79b307a78b8721328ff0e73931710bd6f5ec77f72bda0e6b092ae6962' 
  AND token = 'YvY5g+5xRdSWi97aMN2iMmyY9rd0wSGoN0i0Nn1Qd0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}