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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11cb26d1f375c51c9f5d91d28b02974102b77268050fa0cc2b216dd8e118ac21' 
  AND token = 'HX38kcchwB1q4AU7bVm9FbV1kdhRCV+7GlwCvHWJaJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}