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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b0cd4fa151895ed1c047ad8487f1f1f51d8f63a7b8ba97b80b320cc40f4149' 
  AND token = '0HM7D/ylYykBFOiRb1MNJ1SS/eR3JJcIbXoVAXK1DjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}