SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e83cadf676d038f565a6fbff4a8dec0a1204506e3209741541a882823c8b89' 
  AND token = 'jktquCm3MeGO2z2UxalOVjPPFfezBETJJLilRmw48Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}