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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f260575989bcc3b06a72e345c74291a79c966f17e4bb42c522d620422548e1f' 
  AND token = 'HFPoh8YkS5B2crCvBM/yc0aHvBN9pbDnEPG3RB64QXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}