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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5edb8aab4a5c5f1c169c270a7872786d21a3d05625c5e090233aab5fe898ad' 
  AND token = '6jfl/7I6gX1z92eJmEQVWTXUOB3LPkTVp0rQ30obFsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}