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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75184cf2988173b068f997be2152a5c03b7f9d22b06476493a00d9fbfe92e2ed' 
  AND token = '/irP/KNqknDjVdrdMA3GeqL8dWY6ecLe0n64oEio2tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}