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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1a63ba262ba5d36a927ac0529f103025a043c9e2f9e2e652f4a76f3bd8d770' 
  AND token = 'ifWEwSOB/3/vn2xGcAUBvc3zgW2qBgS5RJKNzrHMXBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}