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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c86a9d6e321b54d9c071a8f8608e52baf144163312ec28ab6faad76377ab6f18' 
  AND token = '8O/2REUQVfiwk+XVLNsNdUmmfYvxy6FcS4q8N840SdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}