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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927a55ce8d4de767f814422f5c0729dd0830695236fbffb76955a1c9d7063289' 
  AND token = 'PWvC0w9fTY5DIG/QR10JPurje5R+esBsyxMJKtyDNFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}