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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8cd983a7532a606837a280b7da0ae8d4d599601006a63127e4802f97adf41b0' 
  AND token = 'IrLrbPFiaCOYOqImQY6GYk7eTYQfYTXVqp4y5Y6Ocgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}