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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f571f4db0af583ce4524523bd3e8888fa6f0f27b0b971cbbc6db66bc1a73a9' 
  AND token = 'FSaiPgs91hI0rq1w8Hh5Gr3ngqKsliJp5EO0cFUU9nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}